Human Tissue Biology A464
    Extracellular Matrix and Types of Connective Tissue
     
     

    Dense regular connective tissue is another example of common CT.

    This type gets its name because it occurs in tendons and ligaments, on the outer surface (“capsule”) of some large organs or around skeletal structures.

    • Examine the appearance of tendon. Note the regular parallel arrangement of the collagen fibers and the relative absence of cells other than fibroblasts.

    What is the major difference between dense regular and dense irregular connective tissue?

    Clinical note: Without an adequate supply of vitamin C, as in the nutritional deficiency scurvy, collagen I and II do not polymerize properly, leading to
    • Slow wound healing,
    • Distension of blood vessels,
    • Ease of bruising and
    • Loosening of the teeth and bleeding gums

    Now for specialized connective tissue with reticulin fibers.