Human Tissue Biology A464
    Extracellular Matrix and Types of Connective Tissue
     
     

    Connective tissue supports other tissues and connects all of the body’s tissues and organs together. In contrast to epithelium which is composed mainly of cells, connective tissues (CT) consist of material between or outside of cells, largely fibers and a gel-like ground substance. Cells tend to be widely separated among the masses of fibers and ground substances. The fibers and the ground substance are collective termed the extracellular matrix (ECM). The fibers, composed primarily of collagen or elastin, are responsible for the tensile strength and elasticity of the tissue. The ground substance, substantially composed of hydrated proteoglycans, provides the medium through which dissolved substances pass from capillaries to cells and back.

    Connective tissue is organized with cells and material outside of cells.


    Objectives:

    • Identify and recognize the LM and TEM characteristics of extracellular matrix components, including both ground substances and fibers, and understand their functional significance.
    • Recognize the LM appearance and function of the major cell types normally found in the different types of connective tissue
    • Recognize the traditional types of connective/support tissue and their functional significance

     

    Extracellular matrix