Human Tissue Biology A464
    Immune and Lymphatic System
     
     

    Mucosa-associated Lymphoid Tissue (MALT)

    Examine a section of tonsil. Identify the stratified squamous epithelium covering the tonsil and the dense connective tissue at its base. Identify the large lymphoid follicles. The large, pale cells scattered among the lymphocytes in the follicles are macrophages acting as antigen-presenting cells.

     

    Clinical note: Tonsillitis, pharyngitis, and other upper respiratory tract infections are among the most common problems involving the head and neck. Tonsillectomies, which were formerly much more common than now, may be required if chronic tonsillitis causes enlargement of the affected structures to the degree that air passages are obstructed. To the right we see a pair of very large and inflamed tonsils.

    Examine the connective tissue in the wall of the ileum and identify the nodule of lymphoid tissue representing a Peyer's patch. Similar diffuse nodules of various sizes will be seen in sections of esophagus and many regions of the small and large intestines.

    In what sense is the MALT system the first line of the body’s defense?

    Does it resemble more closely a lymph node or a thymus?

    The spleen is next.