Human Tissue Biology A464
    Immune and Lymphatic System
     
     

    Splenic blood supply continued.

    Try to find central arterioles associated with the white pulp lymphoid follicles (periarteriolar lymphoid sheathes or PALS), as well as the marginal zone of these follicles.

    In the red pulp, see if you can  identify the splenic cords (of Billroth), seen at lower right, and the venous sinuses. The latter can be detected by their contents of red blood cells. Try to find a vascular sinus showing the unusual nature of the lining endothelial cells or stave cells.

    It may help your understanding of splenic function by tracing the unusual path of blood in the spleen (through the arteries and into the venous sinuses).

     

    In what sense is blood filtered as it moves through the spleen?

     

     

    Next is the skin.