Cytoplasmic
Organization and Organelles
Rough endoplasmic reticulum (rER)
consists of a network of rounded or flattened membranous sacs (cisternae)
with polyribosomes covering much of the outer surface of the
cisternae Polypeptides synthesized on these ribosomes are deposited
inside the sacs for eventual delivery outside the plasma membrane.
Since the RNA associated with rER is
basophilic, cytoplasm rich in rER shows basophilia with routine LM
stains, such as H&E. This is prominent in neurons, where the
basophilic patches in the cytoplasm are called Nissl or
chromatophilic substance. Basophilic rER is also prominent in secretory
cells, where it is sometimes called ergastoplasm. An example of this
occurs near the nucleus of cells in the pancreas ).
For what reason are
polyribosomes attached to the endoplasmic reticulum in RER?
Smooth
endoplasmic reticulum. |