Peptic Ulcer Disease
 
Symptoms & History

Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

Peptic ulcers are chronic, solitary ulcerations of the GI tract mucosa. 
  • They represent an imbalance between the protective and reparative forces of the gut and the digestive and destructive elements.
  • Approximately 4 million people in the US have peptic ulcers.
  • About 3,000 people die each year as a result of peptic ulcer disease.
  • The lifetime chance of developing a peptic ulcer is 10% for men and 4% for women.
  • They can occur at any level of the GI tract, but most frequent sites are (1) first portion of the duodenum and (2) antrum of the stomach.
  • The bacteria Helicobacter pylori and the use of non-steriodal anti-inflammatory drugs are two of the most important contributing factors in ulcer formation.
The presumed role of Helicobacter pylori.
 

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