Symptoms
& History
Physical
Findings
Stop
& Think
Lab
and X-Ray
Differential
Diagnosis
The
Disease
Treatment
Conclusions
Quiz
& Evaluation |
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Peptic
ulcers are chronic, solitary ulcerations of the GI tract mucosa.
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They represent an imbalance
between the protective and reparative forces of the gut and the digestive
and destructive elements.
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Approximately 4 million people
in the US have peptic ulcers.
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About 3,000 people die each
year as a result of peptic ulcer disease.
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The lifetime chance of developing
a peptic ulcer is 10% for men and 4% for women.
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They can occur at any level
of the GI tract, but most frequent sites are (1) first portion of the duodenum
and (2) antrum of the stomach.
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The bacteria Helicobacter
pylori and the use of non-steriodal anti-inflammatory drugs are two
of the most important contributing factors in ulcer formation.
The presumed role of Helicobacter
pylori. |
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