Malignant transformation?
 
Symptoms & History

Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

Gastric ulcers virtually never "cancerate," but cancers of the stomach often ulcerate.
  • Malignant transformation is unknown in duodenal ulcers.
  • Malignant transformation is vanishingly rare in gastric ulcers. 
  • In those case of supposed malignant transformation, most are doubtless occult carcinomas that ulcerated.


The underlying tendency toward dysplasia and malignancy relates to the association with chronic gastritis, rather than ulcer formation itself.

  • H. pylori may well play an important role in the development of gastric carcinoma, but this tendency stems from the chronic gastritis.
Treatment
 

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