Categories include drugs that inhibit
viral binding and cell entry, reverse transcriptase inhibitors, protein cleavage
and viral assembly.
Co-receptor inhibitors (Selzentry)
Fusion inhibitors (Fuzeon)
Reverse transcriptase inhibitors
- Nucleotide analogs:
AZT, ddI, ddc, d4T, 3TC
- Non-nucleotide analog inhibitors: Lamivudine
Integrase inhibitor (Raltgravir)
Protease inhibitors prevent
cleavage of master viral protein into submits necessary for viral assembly.
- Saquinavir, Indinavir, Nelfnavir
Combination therapy can reduce
the plasma viral load by a 1000-fold over mono drug therapies. |