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General
and Systemic Histopathology, C601&C602
Virtual Slide: This 48-year-old man complains
of fever and oral ulcers.
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This
48-year-old man is seen for a fever of 3 days duration and oral ulcerations,
bleeding gums and a sore throat. He also indicates ease of fatigue and
bruisability. Physical exams reveals an apprehensive, pale man with oozing
gums, oral ulcerations and numerous bruises of the lower legs. He is febrile,
has a tachycardia and an increased respiration rate. There is no oragnomegaly
and no adenopathy.
| WBC 47 X 103 |
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RBC 3.08 |
Uric acid 10 mg/dL |
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Percent |
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HGB 10.4 |
LDH 250 IU/L |
| NE 19.7 |
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HCT 24.9 |
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| LY
1.8 |
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MCV 80.8 |
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| MO
40 |
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MCH 33.7 |
Reference values? |
| EO
0 |
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MCHC 41.6 |
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| BA
0 |
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RDW 15.6 |
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| Blasts 38.5 |
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PLT 119 X 103 |
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MPV 7.0 |
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Click the little red + in the smear above to see the slide using the virtual
microscope. Describe what you see and then answer the following questions.
- What is a leukemia?
- How are acute leukemias classified?
- What do you think the bone marrow looks
like?
- What is an Auer rod and what does it
mean?
- How to distinguish ALL form AML?
- What blood and urine test will help
distinguish acute monocytic leukemia from acute granulocytic?
- Why the oral ulcers and easy of
bruising?
The next patient is a listless 5 year-old. |
This picture is from another patient with a similar but different form of
this disease |
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