General
and Systemic Histopathology, C601&C602
Slide 100: Lung with pulmonary hypertension
and embolus
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The changes are subtle
in this tissue. Look at the smaller muscular arteries for the hyperplastic
changes. It might be wise to review normal lung to get an idea of what
these vessels should look like before tackling this slide.
See this slide with the
virtual microscope. |
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There are actually
two things of interest in this slide. First, notice the thickened muscular
walls of the smaller arteries and arterioles; changes of pulmonary hypertension.
The pulmonary vessels are undergoing hyperplasia to "adapt" to higher than
normal pulmonary vascular pressures. This feature contributes to the resistance
in the pulmonary vascular bed, and will lead to right-sided heart failure.
What are some causes of increased pulmonary vascular
pressure
? Also, note the pulmonary emboli. Could these be thrombi? What is the difference? |
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