WBCs

• The Basics
• Reactive
• Leukemic

• The Basics
• Diseases

Sources of Error

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Quiz Please

• Lymphocytosis is the hallmark of a viral infection.
• No, we don't use the term right-shifted differential.
• Many of the lymphocytes will demonstrate reactive features, which we unfortunately referred to as "atypical changes."
• We now reserve the term "atypical" for disturbances in maturation, even suggesting (dysplasia). Unfortunately, this misapplied term will be with us for a long time.
• As with the rise in PMNs with a bacterial infection, the lymphocytosis of a viral infection can be striking. Values of up to 20,000 are possible.
• Mononucleosis is the quintessential example. The irony is that the cells for which this disease is named are actually lymphocytes and not monocytes at all.

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