Mr. Harvey's Seizure
 
Symptoms & History

Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation


Mr. Harvey had a rather complicated problem. Obviously, his clinical course sure didn't work out too well.
  • History and physical is where it all starts.
  • His diabetes resulted from high cortisol levels.
  • The increasing cortisol led to changes in his insulin requirement.
  • His adrenals were hyperactive because they were caught up in a paraneoplastic syndrome secondary to ACTH secretion by a small cell carcinoma.
  • Small cell carcinomas arise from neuroendocrine cells, unlike the common variety of lung cancer, squamous cell carcinoma.
  • The overall picture undoubtedly contributed to an increased susceptibility to infections.
  • Focal bronchial obstruction by his tumor created the right local circumstances for the pneumonia to start.
  • Unfortunately, the bug happened to be a methycillin resistant Staphylococcus aureus.
He died. Did we do a lousy job ?                             Back
 

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