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General and Systemic Histopathology, C601&C602
     
    Slide 10: Colloid Goiter of Thyroid
     
     
    In this scan of the tissue you can easily see how enlarged some of the follicles are.

    See this slide with the virtual microscope.

    Note the large follicles filled with colloid. The follicles are lined by lazy looking follicular cells. This thyroid is fairly sleepy. You may see some inflammation in areas, but for the most part an inflammatory infiltrate is not a part of this lesion. The cleared areas at the edges of the colloid represent dehydration changes of the colloid during tissue processing, and not part of any pathology. What are some of the causes of this condition? What do you do to diagnose it? Will the thyroid function studies be abnormal? Would a needle aspiration help?


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