Clinical Case: Mrs. Johnson's Vaginal Bleeding
 
Symptoms & History

Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

In summary
  • Cervical cancer and it's precursors develop over a period of time, in most cases it takes years.
  • HPV types 16, 18 and 33 are important in development.
  • Most, but not all cases, are squamous cell cancers.
  • Stage is crucial to predicting outcome and designing trx.
  • Local extension plays an important role in mortality.
    • Renal failure from ureteral compression and bladder involvement.
  • Survival rates:
    • Stage I: 80-90%
    • Stage II: 75%
    • Stage III: 35%
    • Stage IV: 10-15%
  • Screening and early detection is the key.
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