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General and Systemic Histopathology, C601&C602
     
    Slide 124: Spleen with Amyloidosis


    Just looking at this slide, it's easy to understand how functionless it must have been.  I think it's easy to see the extensive parenchymal deposition of the amyloid protein.  That's what you're looking for.

    See this slide with the virtual microscope.

    Not much to add to the picture. The amyloid material is diffusely spread throughout the splenic parenchyma. You might want to compare this slide to a normal spleen to see how involved it is. Take this time to consider all the places you can see amyloid accumulate. What are the basic forms of amyloidosis?


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