General and Systemic Histopathology, C601&C602 Slide 108: Lung with pulmonary embolus Paradoxical embolization: A paradoxical embolus
is a blood clot that originates in the venous circulation, but actually
ends up on the arterial side. It may cause a stroke or some other arterial
side vascular infarct. How? You know it can't squeeze through the pulmonary
circulation and come squirting out the aortic valve. Therefore it must
have a direct path from the vena cave into the left side of the heart.
And in a reasonable number of people one exists. Specifically an atrial
septal defect. In this scenario, the embolus comes into the right atrium,
but shoots through the atrial septal defect into the left and atrium and
then out aortic outflow tract. Did you figure it out?
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