Discussion
 
Symptoms & History

Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation
 

Transmission and infection

Transmission by virus or infected lymphocytes
  • No casual contact transmission
  • Enters through mucosa (vaginal, rectal, oral)
  • Direct blood inoculation with contaminated needle
From mucosal entry
  • Virus is carried to regional lymph nodes by Langerhans (dendritic) cells.
  • Replication in lymph node proceeds, viruses infect other lymphoid tissues.
Direct Blood inoculation
  • viruses are rapidly cleared by spleen and lymph nodes
  • replication begins
HIV life cycle.          Back
 

 

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