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General
and Systemic Histopathology, C601&C602
Virtual Slide: A 32-year-old white man is
referred because of abnormal CBC
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This 32
year-old white man was referred because of an abnormal CBC that was part of
his pre-employment physical at a local school. His only complaints were
weight loss and fatigue. Physical exam reveals a pale, thin and apprehensive
young man. He experienced mild LUQ abdominal pain during the exam, and his
spleen was enlarged. No adenopathy was observed.
| WBC 89.1 X 103 |
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RBC 2.85 |
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Percent Abs |
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HGB 8.4 |
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| NE 89.5
79.8 |
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HCT 23.9 |
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| LY 5.6
5.0 |
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MCV 83.8 |
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| MO 2.3
2.0 |
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MCH 29.6 |
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| EO 2.6
2.3 |
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MCHC 35.3 |
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| BA
0 0 |
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RDW 15.8 |
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| Many immature cells |
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PLT 565 X
103 |
Reference values? |
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MPV 8.4 |
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Click the red + in the smear above to see the slide using the virtual
microscope. Describe what you see and then answer the following questions.
- Define a myelproliferative disorder (MPD).
- What's the most likely diagnosis here?
- How would you confirm it?
- What is the PH1
chromosome?
- In what cells do you find it?
- Click the image to the right for more
info.
- What would the marrow look like.
- What's with his big spleen?
- What would a serum vitamin B12
show?
The next patient complains of
fever. |
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