General and Systemic Histopathology, C601&C602
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Note that you can actually
see the areas of papillary carcinoma just by looking at the tissue on the
slide. You will also see many lymphoid aggregates within the surrounding
thyroid tissue. This may reflect some overall excitement on the part
of the immune system or may indicate a coexisting thyroiditis. See this slide with the virtual microscope. |
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This picture pretty well says it all. You will see papillary groups of fibrovascular tissue surfaced with cuboidal or columnar epithelial cells. The epithelial cells covering these papillary fronds are the malignant follicular cells. They perceive the space between the papillary groups as the follicular lumen, although they are not making much in the way of colloid. You will likely see some scarring and a few chronic inflammatory cells in association with the tumor. |