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General and Systemic Histopathology, C601&C602
     
    Slide 44: Myocardial infarction with mural thrombus
    What remains of the heart muscle in this case is just a little band of connective tissue. No, you won't find much in the way of myocardium.  Note the mural thrombus on the endocardial surface.  What do you think happens if part of this should break free?

    See this slide with the virtual microscope.

    As you know by now, always try to spot the area of disease on the slide before going to the microscope. This slide demonstrates a common problem with myocardial infarcts; the formation of "mural thrombus." That is the formation of a blood clot on the endothelium of the heart in the region of the infarct. This may happen rapidly, and probably occurs because of the release of platelet activating agents at the site of the infarct. 


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