Slide B

General and Systemic Histopathology, C601&C602

Virtual Slide: This 20 year-old female college student complains of a sore throat

This 20 year-old female college student has been in good health all her life, but developed a fever and sore throat 2 days ago. Physical exam reveals a red and injected throat with tonsilar enlargement and exudate. There are several enlarged and tender cervical lymph nodes.

WBC 8.4 X 10³	RBC 4.5	Cold Agglutinin Neg
Percent	HGB 13.2	Heterophile Pos
NE 42	HCT 42
LY 30	MCV 80
MO 10	MCH 25.2
EO 3	MCHC 27.2
BA 1	RDW 10.1
Atypical lymphs 14	PLT 210 X 10³	Reference values?
	MPV 7.2

Click the green box in the smear above to see the slide using the virtual microscope. Describe what you see and then answer the following questions.

The WBC changes in this woman's blood smear are consistent with what?

Are they diagnostic?

The agent?
What's with the heterophile test?

Anything more specific?

What of potential long-term complications?

Short-term concerns?

What's the deal with these cells?

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Mark Braun, MD braunm@indiana.edu