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General and Systemic Histopathology, C601&C602
     
    Slide 43: Heart with Myocardial Infarction
     
     
    There's a lot to be seen in this piece of tissue. We have more or less normal heart tissue right beneath the endocardium.  There are several myocardial infarctions of various ages and demonstrating various stages of development. In this picture, the areas identified as "resolving infarct" consist mostly of granulation tissue and represent an infarction of about two to three weeks duration.  The bright pink areas represent a second and much more recent infarction. After you've read the section on myocardial infarctions, see if you can establish the duration of this second one.  What do you think was the most likely cause of death? 

     

    See this slide with the virtual microscope.

    By this time it should be obvious that a lot can be learned from a slide without using the microscope. See if you can find the area of infarction before putting the slide on the stage of your microscope. Hold it to the light or put it on a white background. This area of infarction is about two weeks old, and shows substantial removal of the dead muscle with early replacement with granulation and fibro-connective tissue. Some inflammatory cells remain. This person died with an arrhythmia. 


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