General and Systemic Histopathology, C601&C602
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Here just looking at
the tissue on the slide, you can see the evolving nodular pattern so characteristic
of cirrhosis. See this slide with the virtual microscope. |
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This slide shows all of the features of cirrhosis. You can probably see the degree of nodularity best by first looking at this slide on a white background before going to the microscope. Observe the "bridging fibrosis" between the triads and the loss of definition of the limiting plate of the triads. There is still much inflammation. Note the "regenerating nodules." These nodules are isolated from the biliary system and represent an effort by liver to repair damage, but it's clearly uncoordinated and ineffective. The deranged vascular flow will ultimately become a major problem for those with cirrhosis. |