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General and Systemic Histopathology, C601&C602
     
    Slide 47: Liver with metastatic cancer
     
     
    As with slides of this sort, look at the uninvolved liver first and then move to the region of pathology.  The metastatic focus is pretty easy to recognize.  See if you can detect a glandular or "Indian file" pattern.

    See this slide with the virtual microscope.

    Again, looking at this slide on a white background will show the areas of cancer quite nicely. I believe this is an example of metastatic breast cancer. You will see rudimentary attempts to form glands by the malignant cells. Observe the advancing margins of the tumors. Compare the cytology of the foreign malignant cells to that of the surrounding healthy liver cells. Do you see vacuoles in the metastatic malignant cells?


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