General and Systemic Histopathology, C601&C602
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The areas of splenic
involvement are pretty obvious here, but this isn't always the case.
Look at the uninvolved spleen first to get oriented and then focus on the
areas of tumor. See this slide with the virtual microscope. |
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A higher power view of the focus of Hodgkin's disease. Note the background and especially the great number of eosinophils. The Reed-Sternberg cells should be easy to find. Clearly, this assumes you are looking in the area of the tumor. Don't go straight to high power, you may be way off the mark. |