General and Systemic Histopathology, C601&C602
|
Look for the malignant infiltrate in the triads of the liver and in the sinusoids of the spleen. |
|
The changes in the spleen are very subtle. You will see a bland looking diffuse infiltrate in the parenchyma as well as "cuffing" of lymphocytes around some of the vessels. It would be good to look at sections of a normal adult spleen first to know what it is supposed to look like. Then concentrate on the areas around the smaller blood vessels. |