General and Systemic Histopathology, C601&C602
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The clusters of dysplastic cells are fairly
numerous although you will need to search for them. You will see many normal
squamous epithelial cells with small, point-like, central nuclei. The dysplastic
cells have a large nucleus with irregular nuclear borders and irregular nuclear
clumping. See this slide with the virtual microscope. |
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Here you can see the nuclear atypia of the dysplatic cells. Large and immature appearing nuclei, irregular nuclear borders and clumping of the DNA. |