General and Systemic Histopathology, C601&C602
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Look carefully at the
lung tissue for the little pink areas of caseous necrosis. These are the
areas of tubercular infection. They don't show a well developed granuloma
architecture, but you'll see the evolving features and should have no trouble
finding the giant cells. See this slide with the virtual microscope. Compare these granulomas with those of sarcoid. |
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This picture details two of the giant cells associated with one of the granulomas. You can see the peripheral array pattern of the nuclei in the larger one. The age of this slide has contributed to the "hot pink" staining quality. Other than the accentuation of the eosinophilic property of the stain, this slide is very good representation of the tubercular process. |