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General and Systemic Histopathology, C601&C602
     
    Slide 68: Lung with bone marrow embolus
     
     
    This stuff is hard to find, but once you see it you'll know what we're talking about.  These are microscopic sized fragments of bone marrow, so don't expect to see them with the unaided eye.  What's more, be prepared to look at a number of areas to find this alteration.

    See this slide with the virtual microscope.

    Look in the smaller blood vessels of this section of lung. You will see small fragments of fat and hematopoietic tissue. These are little, intact, fragments of bone marrow that were dislodged because this patient sustained major long bone fractures in an auto accident. Some of the bone marrow gained entrance into the circulatory system, and then became lodged in the lung vasculature. This person died shortly after the event. Can you imagine other conditions that could cause this?


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