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General and Systemic Histopathology, C601&C602
     
    Slide 79: Kidney with chronic pyelonephritis
     
     
    A higher power view showing one of the more important vascular changes often associated with this condition. These are small vessel changes of hypertension, which speak to the relative degree of hypoxia of the renal tissue. As noted in the first picture of this condition, you will see many chronic inflammatory cells in the interstitial tissue and dilated tubules containing pink staining proteinaceous goo, giving the appearance of thyroid colloid. You should note the scaring in the interstitial tissue in general and to some degree around the around the glomeruli. This is often associated with chronic ischemic injury of the kidney, which worsens as the process proceeds. Think diabetes and hypertension. 

    See this slide with the virtual microscope.


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