General and Systemic Histopathology, C601&C602
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This scan shows quite
nicely the area of tumor with the normal testis at the edge. See if
you can recognize a tubular arrangement of the malignant cells. There
will be a rather marked lymphocytic infiltrate as well. Sometimes this
lymphocytic element is so pronounced that these tumor are occasionally mistaken
for lymphomas. See this slide with the virtual microscope. |
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This picture shows mostly normal testicular parenchyma with only a little tumor at the edge. Note the "watery" appearance of the cytoplasm of the malignant cells and their slight off center vesicular, "fried egg" looking nucleus. You may see the cells in little clusters something like seminiferous tubules. You will see the cells are very monotonous and bear some resemblance to lymphocytes. Because there is often a significant lymphocytic infiltrate along with this lesion, it is sometimes hard to distinguish from a testicular lymphoma. You will see some mitoses, and possibly some embryonic tissues mixed with the seminomatous elements. |