General
and Systemic Histopathology, C601&C602
Slide 156: Pseudosarcoma Protuberans
of Skin
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I don't think you'll
have any trouble seeing the tumor here.
See this slide with the
virtual microscope. |
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This is one of the most
enigmatic and unpredictable tumors of soft tissue. It generally arises
in the dermis, spreads locally and may metastasize to distant organs. Although
fairly slow growing, it is relentless. This is generally considered a localized
form of fibrosarcoma, although it may become aggressive in some circumstances.
Note the highly atypical fibroblasts and especially the "woven mat or storiform"
pattern of the groups of cells. This pattern creates the appearance of
a coarsely woven mat, kind like the type you would you might wipe your
feet on at the front door of your home. You will definitely miss this important
diagnostic feature of this lesion if you are go straight to your high power
objective. Cruise first on low power to see this aspect of the tumor. |
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