General and Systemic Histopathology, C601&C602
    Slide 156: Pseudosarcoma Protuberans of Skin
    I don't think you'll have any trouble seeing the tumor here.

    See this slide with the virtual microscope.

    This is one of the most enigmatic and unpredictable tumors of soft tissue. It generally arises in the dermis, spreads locally and may metastasize to distant organs. Although fairly slow growing, it is relentless. This is generally considered a localized form of fibrosarcoma, although it may become aggressive in some circumstances. Note the highly atypical fibroblasts and especially the "woven mat or storiform" pattern of the groups of cells. This pattern creates the appearance of a coarsely woven mat, kind like the type you would you might wipe your feet on at the front door of your home. You will definitely miss this important diagnostic feature of this lesion if you are go straight to your high power objective. Cruise first on low power to see this aspect of the tumor.

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