Nevocellular Nevus (Pigmented nevus, Mole) Yes, these are all examples of the same lesion. Nevus cells are non-dendritic melanocytes. They occur in aggregates, or nests, along the epidermal-dermal junction or within the dermis. We look for maturation from surface to base. That is, the deeper the clusters are in the dermis, the more compact and mature the individual cells should be. Melanomas, on the other hand, show immature cells through their full thickness. There is no maturation from the surface to base in a melanoma Click here for a microscopic