Ovary -- site of oocyte formation and maturation within follicles

Examine each of the two sections of ovary on slide 13 at low power and observe the number of variety of follicles present (Fig. 22-2). Most follicles are located in the cortex surrounding the medulla. With higher power, identify the capsule with the simple cuboidal surface epithelium and dense irregular supporting tissue stroma. Part of oviduct and well-vascularized mesentery supporting the ovary are also present here. Click image at right for expanded view.

Why are the terms “cortex” and “medulla” poorly suited to the ovary?

Clinical note: Surprisingly, perhaps, ovarian cancer most commonly involves cells of the surface epithelium. When the disrupted epithelium heals after ovulation, epithelial cells can be displaced into the stroma and give rise there to cysts which have the potential to become neoplastic.

On slide 13 identify follicles at various stages of development:

• Primordial follicles,
• Primary follicles,
• Secondary follicles, and
• Mature (Graafian) follicles (Diagram below and Figs. 22-2 through 22-7).
• Within follicles at each stage, identify the features that characterize that stage.

Specifics you should be able to identify.