F605-606 - PRINCIPLES OF PHARMACOLOGY

Class Information and Resources

• Course Objectives
• Faculty
• Text Books
• Examinations and Grading
• Competencies
• Fall Schedule
• Spring Schedule
• Resource List
• Review Questions
• GET YOUR GRADES NOW!
• Audio Lectures

Course Objectives

Course Objectives:  Course objectives are to present the concepts and principles by which drugs produce both therapeutic and toxic actions; to provide an introduction to many of the drugs available to the practicing physician; and to highlight the application of pharmacologic principles to the treatment of disease. Students should be able to understand drug action by integrating principles of medical physiology and biochemistry with knowledge of how drugs act on different body systems; to understand how pharmacokinetic parameters may be used to advantage in therapy; to predict how certain drugs based on mechanism of action can affect autonomic nervous system function; to list drugs that affect inflammation; to know the mechanism by which drugs can be used to treat angina, arrhythmia, hypertension and asthma. Students should be able to recognize the importance of selective cell toxicity and its application to chemotherapy of bacterial, mycobacterial, fungal and viral infections as well as neoplastic diseases. Students should be able to describe the major psychotherapeutic agents used to treat anxiety, insomnia, psychoses, and depression; to list drugs that induce narcosis, analgesia and anesthesia; to describe hormone function and drugs that affect the endocrine system as well as agents used to treat derangements of normal function. Students will demonstrate an understanding of the principles of toxicology; and to define how various drugs, toxic metals, pesticides, airborne toxins and household poisons alter normal clinical parameters. 

Association for Medical School Pharmacology Knowledge Objectives in Medical Pharmacology:

http://www.aspet.org/AMSPC/Knowledge_Objectives/default.asp

Faculty

Dr. Watkins will serve as course director.  Students wishing to make appointments may contact the specific instructor.  Daily walk-in hours will be subject to instructor availability.

 *  Students MUST attend each class. Nonattendance will result in a failing grade

Text Books

Textbooks :                 Trevor et al., Katzung & Trevor’s Pharmacology Examination & Board Review, 7^th edition, Lange Medical Books / McGraw Hill, 2005. 

                                    Mycek et al., Lippincott’s Illustrated Review of Pharmacology, 2nd_eedition special millennium update, Lippincott Williams and Wilkins, 2006. 

Reference Texts:       A to Z Drug Facts, 6^th edition, Lippincott Williams & Wilkins, 2006.
 
2008 Physicians Desk Reference, 2007.

Course Web Site:       http://medsci.indiana.edu/pharm/default.htm

Examinations and Grading:

Examinations and Grading: 

• 3 two-hour 140 point exams will be given each semester. These will consist of 60 two-point questions (choose the one best answer) and other types of questions (problems, short answer, essays, etc.) worth 20 points.
   
• 1 three-hour cumulative 200 point semester final will be given in December. This will consist of 100 two-point questions (choose the one best answer).
   
• As a comprehensive final examination the NBME shelf exam will be administered in May. The results will contribute 20% of the final course grade. Students MUST achieve a score above the 5^th percentile on this exam in order to pass the course.
   
• There will be daily pop quizzes during the fall and spring semesters that are worth 4 points each. There will be no makeup on quizzes.  Other exercises may be included at the discretion of individual instructors for which a modest number of additional points may be awarded.

The anticipated grading scale will be 90%-100% - Honors; 80%-89% - High Pass; 70%-79% - Pass; 69% - DF and below 69% - Fail.  Final grades will be determined based on total points. Students scoring less than 70% on any exam are strongly encouraged to make an appointment to discuss their performance on the exam with the appropriate instructors.

Graduate Students will be assigned a letter grade at the end of each semester.  The anticipated grading scale will be 87%-100% - A; 75%-86% - B; 70%-74% - C; and below 70% - Fail.  Final grades will be determined based on total points.  Students scoring less than 75% on any exam are strongly encouraged to make an appointment to discuss their exam with the appropriate instructors.

PLEASE NOTE:  Typically, at the end of class on the second day following the exam, the instructors will provide the student's score, a ranking of how the student performed on the exam, and the student's ranking in the course.  This information will be available on our web site.  Exams will be stored in the office.  Students wishing to look over their exams may make an appointment with the appropriate instructor. 

 ·        Exams must be handed in to an instructor, who will check the student's name off the class roster. 

·        Only one student at a time may, after leaving their exam with an instructor, be excused to go to the restroom during the exam period. 

·        Do not open exams until all students have received their exams and you are instructed to do so.

·        Cheating will not be tolerated.  Any student alleged to have cheated on an exam will be reported to the School of Medicine Student Promotions Committee.

Assessment of the Competencies in Pharmacology

Fall Course Schedule:

PHARMACOLOGY F605

FALL 2007

8:00 -- 9:55 MW

Spring Course Schedule:

PHARMACOLOGY F606

SPRING 2008

8:30 -- 9:55 MW

Audio Lectures: introduction; pharmcodynamics; pharmacokinetics1; pharmacokinetics2; drug testing; prescriptions; cholinomimetics; ACHE inhibitors;anticholinergic; sympatholytics   ;  angina-CHF; diuretics; hypertension;  asthma;   anticoagulants; lipids;   penicillin; bosin10-17; bosin10-22a; bosin10-22b; bosin10-24a; bosin10-24b; bosin  10-29a; bosin 10-29b; bosin 10-31a; bosin 10-29b ; bosin 11-7a; bosin 11-7b; bosin 11-12a; bosin 11-12b; bosin 11-14a; bosin 11-14b; bosin 11-19a; bosin 11-19b; bosin 11-26b; bosin 11-28