Human Tissue Biology A464
    Digestive System, The Stomach
     
     

    Stomach -- site where food is converted to a thick fluid for most efficient enzymatic digestion of macromolecules.

    Examine a section of the fundic region of the stomach.

    • Identify first the layers and sublayers, noting that the simple columnar epithelium invaginates into gastric pits, which are tightly packed together side-by-side
    • These lead into the gastric glands which extend down all the way to the thin muscularis mucosa. Cells of the lamina propria are seen scattered loosely around the gastric pits.

    What is the function of each epithelial cell type in the stomach?

    Starting at the surface, identify the mucus-secreting cells (called surface and neck cells depending on their proximity to the surface lining the stomach cavity), the large eosinophilic parietal cells, and the smaller, more basophilic peptic cells. (Image courtesy of GERD Information Resource Center)

    Why do you suppose most of these cells are protected down inside the gastric pits/glands?
     

     

    On to the pyloric glands and small intestine.