Clincial note: Despite
keratinization, epidermis is permeable to many low molecular
weight compounds. This allows transdermal
administration of certain drugs, hormones, or nicotine via “skin
patches” and is the basis of contact dermatitis, an example of
which is the skin’s reaction to compounds in the poison ivy plant.
Examine the dermis and hypodermis and identify the different types of tissues present.
See if you can identify Pacinian or lamellated corpuscles.
Examine all the dermal papillae
and identify any Meissner’s or tactile corpuscles present,
although these are sometimes difficult to recognize in routinely
stained sections.
How does the structure of
the lamellated corpuscles match their function?
Clincial note: Despite
keratinization, epidermis is permeable to many low molecular
weight compounds. This allows transdermal
administration of certain drugs, hormones, or nicotine via “skin
patches” and is the basis of contact dermatitis, an example of
which is the skin’s reaction to compounds in the poison ivy plant.