Thin skin -- present on most of the body and similar in many respects to thick skin, but much thinner overall, with hair follicles and without the features for detecting and protecting against pressure/friction.

Examine slides of thin skin:

• Note the differences in thin skin with regard to the dermis and the epidermal strata.
• Identify melanocytes, which are also seen on.

How do you think keratinocytes become pigmented?

Clinical note: Vitiligo is an acquired patchy loss of pigment in the skin, due to a localized autoimmune reaction to the melanocytes.

Now for skin appendages.