| Symptoms
& History
Physical
Findings
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& Think
Lab
and X-Ray
Differential
Diagnosis
The
Disease
Treatment
Conclusions
Quiz
& Evaluation |
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And,
if local destruction and metastatic disease aren't enough, there are always
paraneoplastic
syndromes.
-
Hormones and hormone
like substances produced by the tumor causing remote illness and
symptoms, not related to direct organ invasion by the cancer.
-
Antidiuretic hormone (ADH)
inducing hyponatremia (small cell carcinoma predominately).
-
Adrenocorticotropic hormone
(ACTH) causing Cushing's syndrome (small cell carcinoma
predominately).
-
Parathyroid and parathyroid-related
peptide causing hypercalcemia (squamous cell carcinoma predominately).
-
Calcitonin causing hypocalcemia.
-
Gonadotropins causing
gynecomastia in men (breast development).
-
Serotonin causing carcinoid
syndrome (bronchial adenomas).
-
Eaton-Lambert syndrome.
A myasthenic condition producing muscle weakness.
-
Hypertrophic pulmonary osteoarthropathy
(clubbing of the fingers and toes).
This sounds awful Doc, so how
long do I have?
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