| Symptoms
& History
Physical
Findings
Stop
& Think
Lab
and X-Ray
Differential
Diagnosis
The
Disease
Treatment
Conclusions
Quiz
& Evaluation |
|
Risk
factors for atherosclerosis.
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Genetics: The single
most important predictive element in the development of atherosclerosis.
Bad genes = bad disease.
-
Age: Symptomatic atherosclerosis
increases with age.
-
Sex: Males are more prone
throughout life.
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Hypertension: Accelerates
vascular injury. BP of 169/95 mmHg carries a 5X increased risk over BP
of 140/90.
-
Cigarette smoking: Carbon
monoxide is thought to cause vascular injury. One or more packs a day increases
risk 2X.
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Diabetes: Hyperlipidemia
and other factors increase risk.
-
Elevated plasma homocysteine:
Endothelial dysfunction.
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Factors affecting thrombosis
and platelet aggregation.
-
Hyperlipidemia: Most
significantly hypercholesterolemia.
The
role of cholesterol
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