Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

Hyperplasia of the prostate

• Grossly has a nodular pattern.
• Involves both gland and stromal elements.
• Is benign, i.e. no gland-within-gland or cytologic features of malignancy.
• Has a double layer of glandular epithelium. In other words, there is a basal or reserve layer that gives rise the mature columnar epithelium lining the prostatic glands.
• Probably results from stimulation of dihydrotestosterone, a metabolite of testosterone.