Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

The Gleason grading system is most often used.

• This is a histologic assessment of the tumor, not a description of its spread.
• Five grades based on glandular pattern and degree of differentiation.
• Grade 1 is best differentiated with well developed glandular pattern.
• Grade 5 is least differentiated with no glandular pattern.
• The other grades are in between.
• A tumor is graded on both its best and worst areas of differentiation.
• The two number values are added to give the Gleason's Score.
• For example, a tumor with patterns of both Gleason's 2 and 4 would have a Gleason's Score of 6.