| Symptoms
& History
Physical
Findings
Stop
& Think
Lab
and X-Ray
Differential
Diagnosis
The
Disease
Treatment
Conclusions
Quiz
& Evaluation
|
|
|
Central Nervous System Involvement,
Continued
|
AIDS related cognitive-motor
complex.
-
dementia (mental slowing)
-
memory loss
-
mood disturbances (apathy, depression)
-
motor disturbances (ataxia)
-
bladder and bowel incontinence
-
seizures
Pathologic findings in CNS
involvement.
-
Grossly, there is mild diffuse
atrophy with sulcal widening.
-
Dispersed microglial nodules
seen microscopically.
-
Within the microglial nodules
are macrophage-derived multinucleated giant cells.
-
Microscopic areas of necrosis
with reactive gliosis.
|
Continue
Back |
|