Symptoms
& History
Physical
Findings
Stop
& Think
Lab
and X-Ray
Differential
Diagnosis
The
Disease
Treatment
Conclusions
Quiz
& Evaluation
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Transmission and infection
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Transmission by virus
or infected lymphocytes
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No casual contact transmission
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Enters through mucosa (vaginal,
rectal, oral)
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Direct blood inoculation with
contaminated needle
From mucosal entry
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Virus is carried to regional
lymph nodes by Langerhans (dendritic) cells.
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Replication in lymph node proceeds,
viruses infect other lymphoid tissues.
Direct Blood inoculation
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viruses are rapidly cleared
by spleen and lymph nodes
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replication begins
HIV life
cycle.
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