General and Systemic Histopathology, C601&C602
    Slide 224: Angiosarcoma of breast following breast cancer treatment.  
    This is an unfortunate example of second malignancy arising as a consequence of the treatment of the first one. This is an angiosarcoma that arose in the area of the previous cancer surgery, which was followed by irradiation.

    See this slide with the virtual microscope.

    Throughout this region you will see malignant endothelial cells, some aggregated into vascular structures. RBCs are within the vascular slits, and elsewhere they have been leaked into the surrounding tissue space.

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