Although the breast is subject to every major class of disease, by far cancer is the most significant element we will study. Still you need to be familiar with inflammatory and traumatic lesions, as well as the common benign and malignant tumors. Even today a painless breast mass is often the cause of great of concern. Sophisticated imaging techniques have certainly changed the evaluation of a breast lump, still the ultimate answer rests with the biopsy. In this unit we will be looking at conditions that present as masses or at least relatively well defined areas of abnormality. We will see various forms of breast cancer as well as several favorite methods and routes of spread. Although you won't be able to see the famous estrogen and progesterone receptors with microscope, I might ask you something about them on a slide quiz. Furthermore, don't make the erroneous assumption that breast disease is restricted to women. You want to be sure you know what is meant by the term "gynecomastia" as well as its associated circumstances and agents. 
 

Slide 31, breast skin with Paget's disease.	Slide 31, breast skin with Paget's disease, a higher power view.	Slide 33, skin with metastatic breast cancer in dermis.	Slide 51, duct cell carcinoma of the breast.	Slide 73, fibrocystic disease of the breast.
Slide 96, fibroadenoma of breast.	Slide 111, lymph node with metastatic breast carcinoma.	Slide 111, lymph node with metastatic breast carcinoma.	Slide 158, invasive duct cell carcinoma of the breast.	Slide 158, invasive duct cell carcinoma of the breast, a higher power view .
				I'd like to take the quiz now.
Slide 224, angiosarcoma of the breast	Normal breast		Breast slide overview

Mark Braun, MD braunm@indiana.edu
Copyright 1998, the Trustees of Indiana University