Physical Findings

Stop & Think

Lab and X-Ray

Differential Diagnosis

The Disease

Treatment

Conclusions

Quiz & Evaluation

• Increased exposure to estrogen during menstrual cycle is associated with increased risk.
• Long duration of reproductive life.
• Nulliparity
• Late age of first child
• Ovarian tumors that elaborate estrogen are associated with breast and endometrial cancer.
• Post menopausal replacement and oral contraceptives are low dose and have not been shown to substantially increase the risk of breast cancer.
• It appears the imbalanced and/or prolonged estrogen stimulation of the breast ductal epithelium is significant in development of breast cancer.