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General and Systemic Histopathology, C601&C602
     
    Slide 50: Heart with endocardial fibroelastosis
    Even without the aid of a stain highlighting collagen or elastic tissue, you can see how markedly thickened the endocardium has become.  This process will obviously lead to a significant restriction in the dilation and filling of the ventricles.

    See this slide with the virtual microscope.

    This is an H&E of an uncommon disease; endocardial fibroelastosis. See how markedly thickened the endocardium is and note the extension of fibrous tissue into the superficial myocardium. Slide #119 shows this with a stain that highlights the collagen. This alteration greatly restricts the ability of the heart to fill and pump effectively. 


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