| Symptoms
& History
Physical
Findings
Stop
& Think
Lab
and X-Ray
Differential
Diagnosis
The
Disease
Treatment
Conclusions
Quiz
& Evaluation |
|
Mr.
Harvey has a paraneoplastic syndrome.
-
Clinical
symptoms are related to production of humoral agent, not direct
mass effect of tumor or its metastases.
-
Paraneoplastic
syndromes are seen in about
10% of patients with visceral malignancies.
-
May be
the first manifestation of an occult malignancy.
-
May prove
as clinically significant as the tumor itself.
-
May mimic
metastases or other conditions, thereby delaying proper diagnosis.
-
Categories
of paraneoplastic syndromes:
-
endocrinopathies
-
nerve
and muscle syndromes
-
dermatologic
disorders
-
soft tissue,
osseous and articular changes
-
vascular
and hematologic conditions
-
immunologic
manifestations
Wow, this is fantastic, don't
leave anything out.
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