General
and Systemic Histopathology, C601&C602
Slide 215: Diphtheria myocarditis
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True, this condition is largely, but not
entirely, of historical value today. The fact that almost no child dies of
this disease today is a result of childhood immunizations. Diphtheria is the
"D" in DPTT. Even so, not every kid is immunized, even here in Camelot, so
sporadic cases are seen.
See this slide with the
virtual microscope. |
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You will see an inflammatory infiltrate in
the interstitium as well as some myocardial cell necrosis. Recall that the
bacteria is in the throat and upper airway and the toxin is actually part of a
lysogenic phage. The tremendous degree of necrosis and copious exudate in the
airways often leads to asphyxial death. The pain from the airway inflammation
is said to be excruciating. |
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